Arabian Horse Focus Groups
    > Drugs/Meds 101
        > Drug Rules for AHA Shows - *Original work done by Phanilah*
New Topic    Add Reply

<< Prev Topic |
Author
Comment
fadboo 
ezOP
Posts: 14
(6/7/05 13:59)
Reply

Drug Rules for AHA Shows - *Original work done by Phanilah*
For some brief background:

The AHA is a member of the United States Equestrian Federation (USEF), which is the National Governing Body for equestrian sport in the United States. As such, the AHA follows the drug rules set up by the USEF. The USEF offers members 2 drug rules to select from: the No Foreign Substance Provisions (which means essentially no drugs) and the other option is the Therapeutic Substance Provisions (which means some drugs are permitted to be used). Like the vast majority of USEF members, the AHA follows the Therapeutic Substance Provisions.

For a real short version of what the Therapeutic Substance Provisions allow:

1) limited use of specific non-steroidal anti-inflammatory drugs (NSAIDS) or specific NSAID combinations. NSAIDS are drugs such as: bute, banamine, ketofen, etc.

2) limited use of methocarbamol (more commonly known as Robaxin, a muscle relaxant)

3) limited use of dexamethasone (more commonly known as Azium, a corticosteroid - often used to treat allergic reactions)

4) anabolic steroids are permitted, except for horses 3 and under being shown in breeding/in-hand classes in the Arabian/Half-Arabian/Anglo-Arabian Division

For anyone interested in reading the full text of the Therapeutic Substance Provisions, the rule is quoted below. There is also a link to the general rules section of the USEF rulebook, in case anyone wants to do some additional reading in regard to the rest of the USEF drug policy.

More info to follow, to help people fully understand what the rules mean and how to properly follow them.



Beth
****************************************************************************************************************
GR410-412. Equine Drugs and Medications Provisions Applicable to Therapeutic Substance Groups.

GR410 Equine Drugs and Medications,

The Therapeutic Substance Provisions.

1. No horse and/or pony competing in a Breed or Discipline designated as (or part of) a Therapeutic Substance Group is to be shown in any class at a competition recognized by the Federation (see also GR402.1, last sentence) if it has been administered in any manner or otherwise contains in its tissues, body fluids or excreta a forbidden substance except as provided in GR411. Any horse and/or pony that competes in more than one Breed, Discipline, and/or Group at a competition, one of which is a No Foreign Substance Group, shall be required to be in compliance with the No Foreign Substance Provisions at all times while competing in any and/or all classes and/or divisions at that competition. For purposes of this rule, a forbidden substance is:

a. Any stimulant, depressant, tranquilizer, local anesthetic, psychotropic (mood and/or behavior altering) substance, or drug which might affect the performance of a horse and/or pony (stimulants and/or depressants are defined as substances which stimulate or depress the cardiovascular, respiratory or central nervous systems), or any metabolite and/or analogue of any such substance or drug, except as expressly permitted by this rule.

b. Any corticosteroid present in the plasma of the horse/pony other than dexamethasone (see GR410.5.b. below).

c. Any nonsteroidal anti-inflammatory drug in excess of two present in the plasma or urine of the horse/pony (GR411 does not apply); exception: salicylic acid.

d. Any substance (or metabolite and/or analogue thereof) permitted by this rule in excess of the maximum limit or other restrictions prescribed herein.

e. Any substance (or metabolite and/or analogue thereof), regardless of how harmless or innocuous it might be, which might interfere with the detection of any of the substances defined in (a), (b), (c) or (e) or quantification of substances permitted by this rule.

f. Any anabolic steroid in the breeding/in-hand classes for three-year-olds and under in the Arabian, Half Arabian, and Anglo Arabian Division (GR411 below does not apply).

2. EXHIBITORS, OWNERS, TRAINERS, AND VETERINARIANS ARE CAUTIONED AGAINST THE USE OF MEDICINAL PREPARATIONS, TONICS, PASTES, AND PRODUCTS OF ANY KIND, THE INGREDIENTS AND QUANTITATIVE ANALYSIS OF WHICH ARE NOT SPECIFICALLY KNOWN, AS MANY OF THEM MAY CONTAIN A FORBIDDEN SUBSTANCE.

3. The full use of modern therapeutic measures for the improvement and protection of the health of the horse and/or pony is permitted unless:

a. The substance administered is a stimulant, depressant, tranquilizer, local anesthetic, drug or drug metabolite which might affect the performance of a horse and/or pony or might interfere with the detection of forbidden substances or quantification of permitted substances; or

b. More than two nonsteroidal anti-inflammatory drugs are present in the plasma or urine of the horse/pony (GR411 does not apply); exception: salicylic acid; or

c. The presence of such substance in the blood or urine sample exceeds the maximum limit or other restrictions prescribed herein below.

4. Restrictions concerning the nonsteroidal anti-inflammatory drugs are as follows:

a. The maximum permitted plasma concentraction of diclofenac is 0.005 micrograms per milliliter. EC 11/16/04 Effective 12/1/04

b. The maximum permitted plasma concentration of phenylbutazone is 15.0 micrograms per milliliter.

c. The maximum permitted plasma concentration of flunixin is 1.0 micrograms per milliliter.

d. The maximum permitted plasma concentration of ketoprofen is 0.250 micrograms per milliliter.

e. The maximum permitted plasma concentration of meclofenamic acid is 2.5 micrograms per milliliter.

f. The maximum permitted plasma concentration of naproxen is 40.0 micrograms per milliliter.

g. Upon the approval of eltenac by the FDA, the maximum permitted plasma concentration of eltenac is 0.1 micrograms per milliliter.

h. Not more than two of the substances listed in (a) through (f) above are permitted to be present in the same plasma or urine sample (GR411 does not apply).

i. Phenylbutazone and flunixin are not permitted to be present in the same plasma or urine sample (GR411 does not apply).

j. Any nonsteroidal anti-inflammatory drug not listed in (a) through (e) above is forbidden to be present in the plasma or urine sample (GR411 does not apply); exception: salicylic acid.

k. Any nonsteroidal anti-inflammatory drug that becomes approved for use in horses can be added to the list of those permitted, after the completion, review and approval of the needed research.

5. Restrictions concerning other therapeutic substances are as follows:

a. The maximum permissible plasma concentration of methocarbamol is 4.0 micrograms per milliliter.

b. The maximum permitted plasma concentration of dexamethasone is 0.003 micrograms per milliliter.

6. Thresholds for substances of possible dietary origin are as follows:

a. The maximum permissible urine concentration of theobromine is 2.0 micrograms per milliliter.

7. Additional restrictions concerning particular classes and/or divisions (GR411 does not apply):

a. In the breeding/in-hand classes for three-year-olds and under in the Arabian, Half Arabian, and Anglo Arabian Division, any anabolic steroid is forbidden. (See HOW LONG DRUGS REMAIN DETECTABLE in the current Drugs and Medications Rules Pamphlet for guidelines).

www.usef.org/content/rule...apters.php



MB II Arabians
Colorado
American Foundation Bred
CMK/Fadjur/Azraff-Ferzon

*****
GAHeC
Colorado Arabian Horse Club
Region 8
fadboo 
ezOP
Posts: 17
(6/7/05 14:06)
Reply

Re: Drug Rules for AHA Shows - *Original work done by Phanil
From: phanilah in response to Message 1 Sent: 3/6/2005 5:25 PM
Side Effects:<o:p ></o:p >

<o:p ></o:p >

“It is this suppression of inflammation and its consequences that has made the corticosteroids such valuable therapeutic agents indeed, at time lifesaving. It is also this property that give them a nearly unique potential for therapeutic disaster”.<o:p ></o:p >

- Philip Swann, BSc, Phd:

<o:p ></o:p >

To help prevent negative side effects, the strategy is to use the lowest effective dosage for the shortest period of time. When higher doses over longer periods are required, it is advised to withdraw slowly, by reducing the dosage over a period of time. Side effects dependent on the dose and duration of treatment.<o:p ></o:p >

<o:p ></o:p >

Because inflammation is an important part of the body’s ability to fight infection, the use of corticosteroids (SAIDs) can decrease the body’s ability to fight bacterial, viral and parasitic infections (as well as mask an increase in temperature). In addition, the suppression of the immune system (how SAIDs control allergic reactions) can also effect the body’s ability to defend itself against infection and delay healing. To tie in with this, because of the use of corticosteroids inhibits macrophage and fibroblast cell response for repairing injured tissue, the effect of impeding normal tissue metabolism in a joint can slow/prevent normal process of repairing tissue damage.<o:p ></o:p >

<o:p ></o:p >

Laminitis is also a very real risk of corticosteroid use, especially with synthetic corticosteroids. The higher the dose of potent corticosteroids, the more likely this toxicity is to happen.<o:p ></o:p >

<o:p ></o:p >

The use of high dose SAIDs for prolonged periods of time can also damage the adrenal glands, cause muscle atrophy and cause (or worsen) gastro-intestinal ulcers. Damage to the adrenal glands can effect the body’s ability to produce the required natural amounts, resulting in drug dependency. <o:p ></o:p >

<o:p ></o:p >

The more common side effects of corticosteroid use are increased water consumption, increase urine production and increase appetite, while at the same time causing the body to retain extra sodium and excrete calcium and potassium. The imbalance of sodium:p otassium/calcium can cause cramping and muscular weakness. <o:p ></o:p >

<o:p ></o:p >



Special Considerations:<o:p ></o:p >

<o:p ></o:p >

Cushing’s Disease – caused by excess corticosteroids<o:p ></o:p >

Addison’s Disease – caused by insufficient mineralcorticoids and sometime glucocorticoids.<o:p ></o:p >

- Both diseases can be fatal and can occur from overuse/abrupt withdrawal after prolonged use of corticosteroids.<o:p ></o:p >

<o:p ></o:p >

Do not give corticosteroids with vaccines, due to effects on immune system<o:p ></o:p >

<o:p ></o:p >

Do not give corticosteroids with eye ulcerations – due to delayed healing properties<o:p ></o:p >

<o:p ></o:p >

Corticosteroids can be used to help control growth of proud flesh (granulation tissue) – the use of corticosteroids a few days after the wound has occurred should have no adverse effect on healing.<o:p ></o:p >

<o:p ></o:p >

Pregnant mares – avoid giving corticosteroids during pregnancy – excessive levels may cause birth defects. Caution should also be taken in giving corticosteroids with later term mares, due to potential to induce labor. <o:p ></o:p >

<o:p ></o:p >

Young foals – avoid use of corticosteroids due to suppression of immune system. When used, often used in conjunction with anti-ulcer medication.<o:p ></o:p >

<o:p ></o:p >

Warning: Corticosteroids + Lasix increases the risk of electrolyte imbalance due to Ca/K losses.<o:p ></o:p >

<o:p ></o:p >

Warning: Corticosteroids and NSAIDs given at the same time may increase the risk of ulcers.<o:p ></o:p >


<o:p ></o:p >

<o:p ></o:p >

<o:p ></o:p >

MB II Arabians
Colorado
American Foundation Bred
CMK/Fadjur/Azraff-Ferzon

*****
GAHeC
Colorado Arabian Horse Club
Region 8
<< Prev Topic |

Add Reply

Email This To a Friend Email This To a Friend
Topic Control Image Topic Commands
Click to receive email notification of replies Click to receive email notification of replies
Click to stop receiving email notification of replies Click to stop receiving email notification of replies
jump to:

- Arabian Horse Focus Groups - Drugs/Meds 101 - Guardian Arabian Horse eClub -

Powered By ezboard® Ver. 7.32
Copyright ©1999-2007 ezboard, Inc.